Department Overview

Clinical Biochemistry department provides a service with a state-of-the-art biochemical investigations of the highest quality to help in the diagnosis and management of disease in the Sultanate of Oman.  This includes highly specialised tests unique for SQUH.

The Department provides clinical biochemistry service to Sultan Qaboos University Hospital on a 24-hour basis and serves as a referral laboratory for hospitals all over the Sultanate. Normal working hours, Saturday to Wednesday is 0800 – 1600 hours. Biomedical Scientists cover hours outside normal working hours in a shift system and a Senior Biomedical Scientist is on-call 24 hours a day. First shift is 0700 – 1500 hours, second shift is 1500 – 2200 hours and third shift is 2200 – 0700 hours.

Metabolic  Screening   section  of Clinical Biochemistry

This section of the department has recently acquired  advanced instruments;  Tandem mass spectrometry (TMS ), High Performance Liquid Chromatography (HPLC), Gas chromatography Mass Spectrometry(GC-MS) and the DELFIA system. This  enables the department to  offer new  service  to patients affected with  Metabolic disorders.  Selective screening for  high risk or affected newborn is performed on Blood spots collected on Guthrie cards (903 Whatman paper) as well as on Plasma and Urine sample.  

 Tandem mass spectrometry (TMS) is used as first line of selective screening for Amino Acids and Acylcarnitines to rule out Amino acids, Organic acid and Fatty acids (short chain, medium chain and long chain) disorders.

High Performance Liquid Chromatography (HPLC) is used for quantitative  analysis of  Plasma , CSF and  Urine  Amino Acids . HPLC is used as a confirmation and monitoring tool for  Amino acids  levels in patients  with amino acids disorders  discovered on screening by TMS .

GC-MS instrument  will soon be in operation for the quantitative analysis of Urine and Plasma  Organic acids.

The DELFIA is a kit based immunoassay instrument and  will be used for Biotenidase, GALT, and other tests.